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The enrolment of male participants only was undertaken in this study [6, 7] to prevent potential bias in the assessment of periodontal parameters given the influence of hormonal fluctuations mainly endogenous oestrogen and progesterone among females that associated with periodontitis [19]

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For instance, if a test detects amphetamines, the MRO will ask whether the individual has a valid prescription for medications like Adderall, which could account for the result